Pathophysiology or physiopathology is a convergence of pathology with physiology. Pathology is the medical discipline that describes conditions typically observed during a disease state, whereas physiology is the biological discipline that describes processes or mechanisms operating within an organism. Pathology describes the abnormal or undesired condition, whereas pathophysiology seeks to explain the physiological processes or mechanisms whereby such condition develops and progresses.
Pathophysiology can also mean the functional changes associated with or resulting from disease or injury. Another definition is the functional changes that accompany a particular disease
Pathophysiology is the study of functional changes in the body that occur in response to disease or injury. For example, if someone ingests a toxin, that toxin might be associated with a variety of physical changes, such as inflammation in the stomach lining or necrosis of the extremities. The field is designed to help people study the progress of disease so that they can quickly identify diseases and consider various treatment options.
This area of study is required for most people who work in the medical profession, including doctors, nurses, and medical technicians. Understanding the progress of disease is key to learning how to identify and treat it, and many medical professionals gain additional skills in the course of their work. A radiologist, for example, often becomes quite adept at identifying the structural changes associated with cancer as a result of viewing hundreds or thousands of films.
There are two separate medical fields involved in pathophysiology. The first is physiology, the study of the body and its functions. The second is pathology, the study of disease and its impact on the body. When combined, students look at how the progress of a disease changes the body, and how the changes can be treated or reversed.
This field of study is not merely academic. Knowing the way in which a disease progresses can allow a medical professional to predict the next stage of a disease, providing appropriate care to the patient. Understanding the ways in which diseases can be treated is also critical, as doctors must choose the best procedures and medications for their patients. Pathophysiology can also be important in end of life care, as healthcare professionals can recognize the signs that a patient is close to the end of his or her life, and they can provide the care needed to keep the patient comfortable.
One of the major issues in this discipline is that every human body is different. What may be normal in one person could be abnormal in another, and diseases will not always behave in exactly the same way. For this reason, it is critical for people in this field to be exposed to a diversity of patients and disease manifestations, so that they see real-world examples of physiological and pathological differences. Failure to be exposed to diversity in medical education can be dangerous for doctors and patients, as it may lead to a missed or erroneous diagnosis.
The branch of science concerned with the chemical and physic-chemical processes and substances which occur within living organisms. the processes and substances with which the science of biochemistry is concerned.
Biochemistry is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Depending on the exact definition of the terms used, molecular biology can be thought of as a branch of biochemistry, or biochemistry as a tool with which to investigate and study molecular biology.
Much of biochemistry deals with the structures, functions and interactions of biological macromolecules, such as proteins, nucleic acids, carbohydrates and lipids, which provide the structure of cells and perform many of the functions associated with life. The chemistry of the cell also depends on the reactions of smaller molecules and ions. These can be inorganic, for example water and metal ions, or organic, for example the amino acids, which are used to synthesize proteins. The mechanisms by which cells harness energy from their environment via chemical reactions are known as metabolism. The findings of biochemistry are applied primarily in medicine, nutrition, and agriculture. In medicine, biochemists investigate the causes and cures of diseases. In nutrition, they study how to maintain health and study the effects of nutritional deficiencies. In agriculture, biochemists investigate soil and fertilizers, and try to discover ways to improve crop cultivation, crop storage and pest control.
- Study of the structure, composition, and chemical reactions of substances in living systems biology chemistry biochemistry.
- Biochemistry origin formation describe function deficiency symptomsenzimes, carbohydrates, proteins, DNA, RNA, etc
- It tries to explain life in terms of bio chemical reactions includes others sciences as anatomy, medicine, agriculture, pharmacy, etc
- Importance of biochemistry in medicine.
- The European Federation for Medicinal Chemistry says the biochemistry is a guide to drug discovery and for its application for example the morphine is a drug that reduces the pain in terminal cancer.
- The biochemistry helps us understand the pathology of any the biochemical changes and related disease is studied physiological alteration in the body through biochemical changes.
- In the present scenario many people rely in taking multivitamin and minerals for better health the function and role of the vitamins is described only by biochemistry.
- There are many disorders due to hormonal imbalance in specially women and children the formation of hormones in the normal body function is taught in biochemistry by which the physician can understand the concerned problem during treatment.
- Importance of biochemistry in Nursing Biochemistry is of great use within the field of nursing, with many practical applications that can assist you in becoming a better nurse.
- Using biochemistry can be helpful knowing the chemical in the nursing profession, allowing reactions of drugs to nurses to determine how much the human body and medicine should be prescribed or mixing said drugs given to each patient they encounter.
- The influence exercised byte environment is reflected both in morphological structure, and chemical structure of organisms. Organic matter is formed, transformed and is degraded in any living organism (plant, animal or microorganism).
- Biochemical processes play an important role in many branches of food industry and especially in the process of processing raw materials, plantar animal kind. Another example are the enzymes involved in various processes which help to improve crops.
- Importance of biochemistry in nutrition for maintenance of health water is necessary optimum intake of many chemicals like vitamins, minerals, essential fatty acids.
- The nutrients value of food material can also Be determined by biochemical tests.
- Importance of biochemistry in pharmacy gives an idea of its constitution Its change of degradation with varying temperature drugs how drugs are metabolized by biochemical reactions in presence of enzymes.
- we need to know in this case the kind of protein based on its function (i.e. Enzyme, receptor, ionic channel, porine, etc.) and as I said before, the interaction between them. Like the rule of key-lock applied to enzymes.
- Some drugs are targeted to metabolism so you need to know each step and know where it’s target. Related with metabolism. You need to know the enzymes involved and how the drug can be metabolized by the Liver known as the First Step Effect. In this process your liver will metabolize the drug and can be good for you (pharmacological effect is maintained) or can be bad (pharmacological effect is inactivated).
- In summary you have to dominate perfectly Biochemistry since knowing the 4 main macromolecules and their functions in the human body and metabolism and how is affected by external factors or malfunction of a enzyme in a metabolic path.
- As a hint, Biochemistry is considered the mother of all the biological sciences. no biochemistry, no medicine, no pharmacy, no immunology, no nothing.